Acute kidney failure occurs when illness, infection, or
injury damages the kidneys. Temporarily, the kidneys cannot adequately remove
fluids and wastes from the body or maintain the proper level of certain kidney-regulated
chemicals in the bloodstream. The kidneys are the body’s natural filtration
system. They perform the critical task of processing approximately 200
quarts of fluid in the bloodstream every 24 hours. Waste products like
urea and toxins, along with excess fluids, are removed from the bloodstream in
the form of urine. Kidney (or renal) failure occurs when kidney
functioning becomes impaired. Fluids and toxins begin to accumulate in the
bloodstream. As fluids build up in the bloodstream, the patient with acute
kidney failure may become puffy and swollen (edematous) in the face,
hands, and feet. Their blood pressure typically begins to rise, and they
may experience fatigue and nausea. Unlike chronic kidney failure, which is long
term and irreversible, acute kidney failure is atemporary condition. With
proper and timely treatment, it can typically be reversed. Often there is no
permanent damage to the kidneys. Acute kidney failure appears most frequently
as a complication of serious illness, like heart failure, liver failure,
dehydration, severe burns, and excessive bleeding (hemorrhage). It may also be
caused by an obstruction to the urinary tract or as a direct result of kidney
disease, injury, or an adverse reaction to a medicine.
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